Job Information
HSS Senior Research Associate in New York, New York
Overview
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Senior Research Associate (PhD)
Crow Lab
Full-Time
Overview:
The focus of our laboratory’s research is defining the biologic mechanisms associated with the pathogenesis of autoimmune disease, with a particular focus on systemic lupus erythematosus. We study cells and immune system products derived primarily from blood samples collected from patients with systemic lupus erythematosus (SLE) as well as other systemic autoimmune diseases and healthy donors. Longitudinal collection of patient samples and their associated clinical data allow for study of those samples that will be particularly informative with regard to identification of patient subsets, molecular pathways and mechanisms involved in risk of disease as well as drivers of immune activation, and biomarkers associated with disease flare. Our long-term goal is to understand the mechanisms of systemic autoimmune disease and identify therapeutic approaches that can ultimately improve patient outcomes.
Specific Duties:
Administration:
Maintain database of all relevant standard operating protocols, lists of reagents, and special techniques used in laboratory studies. Maintain well-organized documentation of all experiments and experimental results relevant to laboratory research.
Participate in weekly laboratory meetings, regularly present research progress, and support the progress of other laboratory staff through helpful suggestions and critique.
Research:
Work closely with PI in the design and execution of translational and mechanism-related research studies.
Apply molecular biology-related skills and techniques to research questions relevant to the mission of the laboratory. Techniques might involve design of protocols for DNA or RNA sequencing and analysis; cloning of genes of interest; expression of recombinant proteins; design and generation of antibodies; transfection of cells with plasmids or siRNAs; isolation of plasma proteins; conduct of in vitro cell culture experiments; development of assays for measurement of plasma proteins.
Collaborate with the senior technician and senior research associate to design and implement studies using patient and healthy donor control samples.
Collaborate with the laboratory’s research assistant in documentation of data related to patient and healthy donor samples.
Maintain written standard operating procedures pertaining to all relevant laboratory assays.
Contribute to preparation of relevant methodology sections of institutional IRB protocols for planned experiments, grant applications, and manuscripts being prepared for publication.
Regularly perform pertinent literature reviews relevant to the mission of the laboratory, and inform laboratory members of relevant advances.
Willingness to gain familiarity with key research questions relevant to rheumatic diseases through participation in HSS academic activities (e.g., research-in-progress seminars, journal clubs).
MINIMUM JOB REQUIREMENTS:
Education/Training:
Bachelor’s degree in molecular and cellular biology, pharmacology, biochemistry, or a related field.
PhD in relevant biology-related field
Postdoctoral experience with demonstrated expertise in molecular biology-related skills.
Experience:
5+ years’ experience in basic translational research, using molecular biology-related techniques.
Proficient use of computers and software, and interpretation of and analysis of data
Qualifications:
The successful candidate must have at least 5 years’ experience in Basic Science/Translational Research, with demonstrated expertise in design and use of molecular biology technques.
Strong organizational, time-management, presentation, and problem-solving skills as well as excellent written and communication skills are essential.
Proficiency in use of computers and software, Microsoft Office Suite, and database experience.
Other Requirements
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Posted Date1 month ago(2/13/2023 3:12 PM)
Job ID2023-17192
LocationUS-NY-New York
CategoryResearch & Academia - All Openings
Emp StatusRegular Full-Time
Hours per Week35
ShiftDays
Minimum Hourly Rate/Annual SalaryUSD $80,000.00/Yr.
Maximum Hourly Rate/Annual SalaryUSD $90,000.00/Yr.