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University of Rochester Staff Scientist, SMD - 229363 in Rochester, New York

Staff Scientist, SMD Job ID 229363

Location School of Medicine & Dentistry Full/Part Time Full-Time Favorite Job Regular/Temporary Regular Opening

Full Time 40 hours Grade 055 Radiation Oncology M&D


8 AM-4:30 PM



The position is a newly-established role in the Laboratory of Radiation Biology in the Wilmot Cancer Institute at the University of Rochester Medical Center. The position is seeking a productive and highly-motivated individual interested in radiation biology, and tumor and normal tissue responses in the irradiated microenvironment. Current studies make use of cultured cells and animal models, and use approaches to understand regulation of tissue responses after irradiation, how these changes alter the microenvironment and drive radiation resistance. The use of radiation is combined with chemotherapeutic agents.

This Staff Scientist position will undertake project development and management at the senior professional level by assuming responsibility for individual research projects that constitute major aspects of several larger research themes in the group. This position will work independently; supervise laboratory technicians, undergraduate students, pre-doctoral students, post-doctoral and medical fellows who join the research laboratory. This individual will remain abreast of current literature in this field and to take the initiative in preparing data for publication in peer-reviewed journals and in presenting this data at major conferences.


This Individual will report directly to the principal investigator, Dr. Brian Marples. This position requires independent judgment in experimental planning and design as well as to the ability to troubleshoot and modify experimental methods accordingly. Furthermore, it will be necessary to accurately interpret results and analyze data to ensure the progression of research projects, and prepare data for publications and contribute to writing manuscripts.


10% Teaching and supervision of graduate students, postdoctoral fellows and laboratory technicians.

10% Data analysis and interpretation with University core facilities and other departments, e.g. Pathology, Flow Cytometry Core, Light microscopy core, Genomics.

5% Continuously update and maintain all state and Institutional regulatory compliance with University Committee on Animal Resource (UCAR), Environmental Health and Safety (EHS) and International Biosafety Committee (IBC).

Project Management (25%)

10% Responsible for designing and executing the studies of preclinical and clinical radiation biology.

10% Develop models of radiation injury; both normal tissues and tumor.

5% Research literature to design and develop methods and resolution of technical problems in the evaluation of the appropriateness of techniques used in experimental protocols.

Bench-top: (50%)

Independently design, perform, troubleshoot and interpret data emerging from experiments in radiation biology, that (1) investigate normal tissue responses after difference dose schedules and temporal responses in acute and chronically responding normal tissues and that (2) investigate mechanisms of radiation damage processing using single cells, 3D culture models and tissues. Animal experiments, breeding and maintenance of mice under development. Tumor grafting, radiation and drug treatment, tumor growth monitoring and tumor and normal tissues harvesting post sacrifice.


Applicants should hold a doctoral degree with 2-5 years of relevant experience. Experience in the biomedical sciences and past small animal work are highly desirable, but applicants with a strong background in a related area of animal work, track-record of accomplishment, and desire to work in a multidisciplinary team of investigators focused on radiation biology will be considered. Candidates should have excellent scientific writing and oral communication skills, as well as the ability to work effectively and collaboratively with others.

How To Apply

All applicants must apply online.

EOE Minorities/Females/Protected Veterans/Disabled